Practically insoluble in water; sparingly soluble in alcohol and in acetone; freely soluble in chloroform and dichloromethane.It is however soluble in alcohol. Alprazolam a fast acting, short duration, benzodiazepine. It is fat soluble. Cannot be snorted or injected or dissolved in water.
which is water soluble, lasts longer, but also takes longer to begin working.
Solubility in mg/mL at 25°: acetone 31, chloroform 15, methanol 8.6, ether 0.7, benzene 0.5, water <0.1.
Source: Clarke’s Analysis of Drugs and Poisons. Electronic edition.
So NO! no it is not, and Xanax tastes horrible if you try to dissolve it in water and drink it…
Anecdotally injection of alprazolam has been reported, causing dangerous damage to blood vessels, closure of blood vessels (embolization) and decay of muscle tissue (rhabdomyolysis).Alprazolam is not very soluble in water—when crushed in water it does not fully dissolve (40 µg/ml of H2O at pH 7). There have also been anecdotal reports of alprazolam being snorted.Due to the low weight of a dose, alprazolam, in one case, was distributed on blotter paper in a manner similar to LSD.
Slang terms for alprazolam vary from place to place. Some of the more common terms are shortened versions of the trade name “Xanax”, such as Xannies (or Xanies); references to their drug classes, such as benzos or downers; or remark upon their shape or color (most commonly a straight, perforated tablet or an oval-shaped pill): bars, ladders, Xanbars, Z-bars, footballs, planks, poles, blues, or blue footballs.